PMLB PDX Core

PDX team

Objectives

  • Create a UHN repository for existing and new tumor PDO and PDX models for use by researchers or public-private partnerships.
  • Establish standard operating protocols to implement best practices for the establishment and use of PDO and PDX models.
  • Provide an integrated data portal linking tumor models with corresponding patients, including clinical annotation, genomics, and experimental data.
  • Offer core services, including training and turnkey studies.

Tumour Type

PDX Models (count)

Lung

>145

Pancreas

>190

Ovarian

>85

Colon

>300

Head & Neck

104

Cervix

20

Mesothelium

13

Metastases

14

Total

>886